페이지 정보작성자 최고관리자 작성일19-06-07 09:56 조회86회 댓글0건
생체모사 카테콜/갈롤 접착소재의 개발과 이의 의공학적 응용
(Nature-inspired approaches in designing novel adhesive biomaterials)
In biomedical applications, adhesive biomaterials are essential at the biointerface between artificial materials and native biomolecules/tissues, and regulate the immune reactions and deformation/denaturation of biomolecules/tissues on the surface of artificial materials. However, the biggest challenge is to develop adhesive biomaterials that maintain water-resistant adhesive properties as well as biocompatibility. In recent years, nature-inspired approaches have emerged to address this challenge. In particular, polymeric biomaterials has been designed by mimicking the unique chemical structures of natural compounds found in mussel foot proteins and plant-flavonoids that show remarkable molecular-level adhesion in aqueous environment. Adhesive biomaterials can be utilized to construct adhesive hydrogels and scaffolds for tissue engineering and surgical applications, and also serve as a molecular glue that binds substrate surfaces and bio-macromolecules, with promising applications in bio-active surface fabrication/modification for in vitro diagnostic devices. In this presentation, the nature-inspired approaches utilizing those adhesive biomaterials for in vivo and in vitro biomedical applications will be discussed.
Seonki Hong, Ph.D.
Department of Emerging Materials Science, DGIST
333 Techno Jungang-Daero, Hyeonpung-myeon, Dalseong-gun, Daegu, 42988, Republic of Korea / E-mail: email@example.com
2015 Ph.D. Department of Chemistry, KAIST
2009 B.S. Department of Chemistry, KAIST
2017 – Assistant Professor, Department of Emerging Materials Science, DGIST
20015 – 2017 Postdoctoral Research Fellow, Center for Systems Biology, Massachusetts General Hospital / Harvard Medical School
20014 – 2015 Predoctoral Research Fellow, Department of Medicine, Brigham and Women’s Hospital / Harvard Medical School
1. Nature-driven adhesive polymeric biomaterials
2. Polyphenol-based multifunctional nanomaterials
3. Biointerface engineering via surface functionalization/modification
4. Simple and rapid in vitro bioassays
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